SET8 Methyltransferase Inhibitor 96 by Cayman Chemical

★★★★☆ 4.0 72 reviews

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Management number 210990470 Release Date 2026/04/04 List Price $36.00 Model Number 210990470
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SET8, a methyltransferase, specifically mono-methylates histone H4 at lysine 20 (H4K20), a process crucial for chromatin structure and gene expression. SET8, included in the kit, transfers a methyl group from S-adenosylmethionine (SAM) to the H4K20 peptide, generating S-adenosylhomocysteine. This is then rapidly converted to urate and hydrogen peroxide (H2O2) using the provided enzyme mix. The produced H2O2 reacts with ADHP to create resorufin, a highly fluorescent compound (excitation 530-540 nm; emission 585-595 nm).

Item Form Powder
Brand Name Cayman Chemical
Manufacturer Cayman Chemical

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